5-Amino-1-MQ

5-Amino-1MQ – 5mg

CAS Number: 42464-96-0
Molecular Formula: C10H11N2I
Molecular Weight: ~286.11 g/mol
Synonyms: 5-Amino-1-methylquinolinium iodide, NNMT Inhibitor 5-Amino-1MQ

Description:
5-Amino-1MQ is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor studied for its role in regulating cellular metabolism and methylation balance. NNMT catalyzes the methylation of nicotinamide, consuming S-adenosylmethionine (SAM) and reducing NAD⁺ availability. By inhibiting NNMT, 5-Amino-1MQ has been shown in research models to elevate NAD⁺ levels, enhance mitochondrial function, and support methyl donor conservation.

Experimental studies have utilized 5-Amino-1MQ to investigate pathways linked to energy expenditure, lipid metabolism, and insulin sensitivity. Its modulation of methylation-dependent cellular processes makes it a useful compound for exploring metabolic dysregulation and aging-related mechanisms.

Form: Lyophilized powder
Amount: 50 mg per vial
Purity: ≥ 98 % (HPLC)
Storage: Store at –20 °C. Protect from light and moisture.
Solubility: Soluble in DMSO, ethanol, or sterile water with gentle warming.

Applications:
For laboratory research use only. Not for human consumption, diagnostic, or therapeutic purposes.

Disclaimer:
All products sold by Xfactor Labs are intended for research use only. Not for human or veterinary use. Not for diagnostic, therapeutic, or cosmetic purposes. By purchasing, you confirm that you are a qualified professional or entity using these materials for lawful scientific research only.